Source Paper
Essential role of brain-derived neurotrophic factor in adult hippocampal function
Lisa M. Monteggia, Michel Barrot, Craig M. Powell, Olivier Berton, Victor Galanis et al.
Proceedings of the National Academy of Sciences • 2004
Morris Water Maze
Objective: Assessment of hippocampal-dependent spatial learning and memory in adult mice with forebrain BDNF deletion
This is a Morris Water Maze protocol using mouse as the model organism. The procedure involves 1 procedural steps. Extracted from a 2004 paper published in Proceedings of the National Academy of Sciences.
Model and subjects
mouse • Not specified in provided text • unknown • adult • Not specified in provided text
Study window
Estimated timing pending
Core workflow
Morris Water Maze Testing
Primary readouts
- Hippocampal-dependent spatial learning performance
- Hippocampal-dependent memory performance
- Long-term potentiation in hippocampus
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Morris Water Maze Testing
Assessment of hippocampal-dependent spatial learning and memory using Morris Water Maze
Note: The provided text is primarily an abstract and header information from a PNAS publication. The actual detailed methods section describing the Morris Water Maze protocol, including specific equipment details, dimensions, procedures, timing, and analysis methods, is not included in the extracted text.
View evidence from paper
“deleting BDNF in broad forebrain regions of adult mice impairs hippocampal-dependent learning”