Morris Water Maze - Reversal Learning
Objective: Evaluation of spatial learning and reversal learning in a water maze task to assess cognitive deficits in Shank3 null mutant mice
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Equipment1
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Protocol Steps
Water Maze Spatial Learning Phase
Mice were tested on initial spatial learning in the water maze task
Note: This phase precedes the reversal learning phase
View evidence from paper
“deficits in reversal of water maze learning were detected only in some cohorts”
Water Maze Reversal Learning Phase
Mice were tested on reversal learning in the water maze, where the platform location is changed from the initial learning phase
Note: Reversal learning deficits were detected only in some cohorts, emphasizing importance of replication
View evidence from paper
“deficits in reversal of water maze learning were detected only in some cohorts, emphasizing the importance of replication analyses”