Source Paper
Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP
You-Ming Lu, Zhengping Jia, Christopher Janus, Jeffrey T. Henderson, Robert Gerlai et al.
Journal of Neuroscience • 1997
Morris Water Maze
Objective: Assessment of spatial learning and memory acquisition in mGluR5 mutant mice using the Morris water maze task
Gather these items before starting the experiment. Check off items as you prepare.
Equipment1
Not specified • Not specified • Not specified • Not specified
1 item available from ConductScience
As an Amazon Associate, we earn from qualifying purchases. Product links help support this free resource.
Protocol Steps
Morris Water Maze Testing
Mutant mice were tested in the Morris water maze to assess spatial learning and memory acquisition
Note: Testing was conducted to examine spatial information acquisition and use in mGluR5 mutant mice
View evidence from paper
“These mutant mice were also impaired in the acquisition and use of spatial information in both the Morris water maze”