Source Paper
Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP
You-Ming Lu, Zhengping Jia, Christopher Janus, Jeffrey T. Henderson, Robert Gerlai et al.
Journal of Neuroscience • 1997
Morris Water Maze
Objective: Assessment of spatial learning and memory acquisition in mGluR5 mutant mice using the Morris water maze task
This is a Morris Water Maze protocol using mouse as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 1997 paper published in Journal of Neuroscience.
Model and subjects
mouse • mGluR5 mutant mice • unknown • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Morris Water Maze Testing
Primary readouts
- Acquisition of spatial information
- Use of spatial information
- Spatial learning performance
- Spatial memory performance
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Morris Water Maze Testing
Mutant mice were tested in the Morris water maze to assess spatial learning and memory acquisition
Note: Testing was conducted to examine spatial information acquisition and use in mGluR5 mutant mice
View evidence from paper
“These mutant mice were also impaired in the acquisition and use of spatial information in both the Morris water maze”