Motor Deficit Assessment
Objective: Evaluation of progressive motor deficits in transgenic mice expressing full-length human mutant huntingtin
This is a Motor Deficit Assessment protocol using mouse as the model organism. The procedure involves 1 procedural steps. Extracted from a 2008 paper published in Journal of Neuroscience.
Model and subjects
mouse • BACHD (bacterial artificial chromosome-mediated transgenic) • unknown • Not specified in provided text • Not specified in provided text
Study window
Estimated timing pending
Core workflow
Motor Deficit Assessment
Primary readouts
- Progressive motor deficits
- Neuronal synaptic dysfunction
- Late-onset selective neuropathology
- Cortical and striatal atrophy
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Motor Deficit Assessment
Evaluation of progressive motor deficits in BACHD transgenic mice
Note: BACHD mice exhibit progressive motor deficits as part of their phenotype
View evidence from paper
“BACHD mice exhibit progressive motor deficits, neuronal synaptic dysfunction, and late-onset selective neuropathology”