Source Paper
Alzheimer's Disease-Like Tau Neuropathology Leads to Memory Deficits and Loss of Functional Synapses in a Novel Mutated Tau Transgenic Mouse without Any Motor Deficits
Katharina Schindowski, Alexis Bretteville, Karelle Leroy, Séverine Bégard, Jean-Pierre Brion et al.
American Journal Of Pathology • 2006
Motor Function Assessment
Objective: Evaluation of motor deficits and motor activity levels across different ages in transgenic mice to assess whether the THY-Tau22 model displays motor dysfunction
This is a Motor Function Assessment protocol using mouse as the model organism. The procedure involves 1 procedural steps. Extracted from a 2006 paper published in American Journal Of Pathology.
Model and subjects
mouse • THY-Tau22 transgenic mice • unknown • Multiple ages investigated (3 months and 10 months mentioned) • Not specified
Study window
Estimated timing pending
Core workflow
Motor Function Assessment
Primary readouts
- Presence or absence of motor deficits
- Motor activity levels
- Changes in motor activity across different ages
Key equipment and reagents
Verified items
0
Direct vendor links
0
Use this page as an execution guide, then fall back to the source paper whenever you need exact exclusions, dosing details, or assay-specific caveats.
Confirm first
- Verify the animal model, intervention setup, and collection timepoints against the source paper.
- Check that every direct vendor link matches the exact specification your lab plans to run.
Use the page like this
- Work through the protocol steps in order and use the inline vendor chips only when you need to source or verify an item.
- Jump to Experimental Context for readouts, data shape, and analysis flow before planning downstream analysis.
Protocol Steps
Start here. The step list is optimized for running the experiment, with direct vendor links available inline when you need to source a cited item.
Motor Function Assessment
Evaluation of motor deficits and motor activity levels in transgenic mice at different ages
Note: Assessment conducted at multiple time points across different ages
View evidence from paper
“There are no signs of motor deficits or changes in motor activity at any age investigated.”