Open Field Test
Objective: Evaluation of exploratory activity, anxiety-like behavior, and locomotor activity in GAT1 knockout mice
This is a Open Field Test protocol using mouse as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 2005 paper published in Journal of Neuroscience.
Model and subjects
mouse • GAT1 knockout (mGAT1 KO) mice • unknown • Not specified • Reduced body weight compared to wild-type (female -10%, male -20%)
Study window
Estimated timing pending
Core workflow
Open-field test administration
Primary readouts
- Delayed exploratory activity
- Reduced rearing
- Reduced visits to the central area
- Total distance traveled
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Open-field test administration
Mice were placed in an open-field arena to assess exploratory behavior, anxiety-like responses, and locomotor activity
Note: The test measured delayed exploratory activity, rearing behavior, visits to central area, and total distance traveled
View evidence from paper
“Open-field tests show delayed exploratory activity, reduced rearing, and reduced visits to the central area, with no change in the total distance traveled”