Source Paper
Mice Lacking the ERK1 Isoform of MAP Kinase Are Unimpaired in Emotional Learning
Joel C. Selcher, Tanya Nekrasova, Richard Paylor, Gary E. Landreth, J. David Sweatt
Learning & Memory • 2001
Open Field Test
Objective: Assessment of locomotor activity and exploratory behavior in a novel open arena to evaluate general behavioral characteristics and activity levels
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Equipment1
Not specified • Not specified • Not specified • Not mentioned
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Protocol Steps
Open Field Test
Place animals in a novel open arena and measure locomotor activity and exploratory behavior
Note: ERK1-null animals showed significantly higher activity levels compared to wild-type littermate controls
View evidence from paper
“The ERK1-null animals demonstrated significantly higher levels of activity in the open field test.”