Source Paper
α7 Nicotinic Receptor Subunits Are Not Necessary for Hippocampal-Dependent Learning or Sensorimotor Gating: A Behavioral Characterization of <i>Acra7</i>-Deficient Mice
Richard Paylor, Michelle Nguyen, Jacqueline N. Crawley, James Patrick, Arthur Beaudet et al.
Learning & Memory • 1998
Open-Field Test
behavioralmouseAcra7 homozygous mutant mice and wild-type littermates
Objective: Assessment of exploratory activity, motor coordination, and anxiety-related behavior in mice
Materials & Equipment Checklist
1 item
Gather these items before starting the experiment. Check off items as you prepare.
Equipment1
Not specified • Not specified • Not specified • Not mentioned
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Protocol Steps
1
Open-field test
Mice were tested in an open-field apparatus to evaluate exploratory activity, motor coordination, and anxiety-related behavior
Not specifiedNot specified
Note: Acra7 mutant mice displayed abnormal anxiety-related behavior in the open-field test compared to wild-type mice
View evidence from paper
“Exploratory activity, motor coordination, and startle habituation were also evaluated. Other behavioral responses in Acra7 mutant mice were also normal, except for an anxiety-related behavior in the open-field test”