Source Paper
Hyperactivity and Intact Hippocampus-Dependent Learning in Mice Lacking the M<sub>1</sub>Muscarinic Acetylcholine Receptor
Tsuyoshi Miyakawa, Masahisa Yamada, Alokesh Duttaroy, Jürgen Wess
Journal of Neuroscience • 2001
Pain Sensitivity Test
Objective: Measurement of nociceptive response and pain sensitivity in mice
This is a Pain Sensitivity Test protocol using mouse as the model organism. The procedure involves 1 procedural steps. Extracted from a 2001 paper published in Journal of Neuroscience.
Model and subjects
mouse • M1 receptor-deficient mice (M1R−/− mice) • unknown • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Pain Sensitivity Assessment
Primary readouts
- Pain sensitivity response
- Nociceptive threshold
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Pain Sensitivity Assessment
Mice were subjected to pain sensitivity testing as part of a comprehensive behavioral test battery to assess nociceptive responses
Note: M1R−/− mice showed no significant impairments in pain sensitivity compared to controls
View evidence from paper
“M1R−/− mice showed no significant impairments in neurological reflexes, motor coordination, pain sensitivity, and prepulse inhibition”