Source Paper
α7 Nicotinic Receptor Subunits Are Not Necessary for Hippocampal-Dependent Learning or Sensorimotor Gating: A Behavioral Characterization of <i>Acra7</i>-Deficient Mice
Richard Paylor, Michelle Nguyen, Jacqueline N. Crawley, James Patrick, Arthur Beaudet et al.
Learning & Memory • 1998
Pavlovian Conditioned Fear Test
behavioralmouseAcra7 homozygous mutant mice and wild-type littermates
Objective: Assessment of contextual and auditory-cue conditioned fear responses in mice to examine the role of α7 nicotinic acetylcholine receptors in learning and memory
Materials & Equipment Checklist
1 item
Gather these items before starting the experiment. Check off items as you prepare.
Equipment1
Not specified • Not specified • Not specified • Not mentioned
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Protocol Steps
1
Pavlovian Conditioned Fear Test
Mice were tested in a Pavlovian conditioned fear test to assess contextual and auditory-cue conditioned fear responses
Not specifiedNot specified
Note: This test was used to examine the role of α7 nAChRs in learning and memory
View evidence from paper
“Acra7 homozygous mutant mice and their wild-type littermates were tested in a Pavlovian conditioned fear test, for spatial learning in the Morris water task, and in the prepulse inhibition paradigm”