Pole Test
Objective: Assessment of motor performance and coordination on a pole as part of a sensorimotor test battery sensitive to nigrostriatal dopaminergic system alterations
This is a Pole Test protocol using mouse as the model organism. The procedure involves 2 procedural steps, 1 equipment items. Extracted from a 2004 paper published in Journal of Neuroscience.
Model and subjects
mouse • wild-type and ASO (alpha-synuclein overexpressing) • male • tested every 2 months for 8 months
Study window
Estimated timing pending
Core workflow
Baseline and Longitudinal Testing Schedule • Pole Test Performance Assessment
Primary readouts
- Motor performance on pole
- Coordination on pole
- Progressive changes in motor function with age
Key equipment and reagents
Verified items
0
Direct vendor links
0
Use this page as an execution guide, then fall back to the source paper whenever you need exact exclusions, dosing details, or assay-specific caveats.
Confirm first
- Verify the animal model, intervention setup, and collection timepoints against the source paper.
- Check that every direct vendor link matches the exact specification your lab plans to run.
Use the page like this
- Work through the protocol steps in order and use the inline vendor chips only when you need to source or verify an item.
- Jump to Experimental Context for readouts, data shape, and analysis flow before planning downstream analysis.
Protocol Steps
Start here. The step list is optimized for running the experiment, with direct vendor links available inline when you need to source a cited item.
Baseline and Longitudinal Testing Schedule
Male wild-type and ASO mice were tested for motor performance and coordination on the pole as part of a sensorimotor test battery
Note: Testing was conducted at multiple timepoints to assess progressive changes in motor function
View evidence from paper
“Male wild-type and ASO mice were tested every 2 months for 8 months for motor performance and coordination on a challenging beam, inverted grid, and pole”
Pole Test Performance Assessment
Mice were assessed on the pole test to measure motor performance and coordination as part of the sensorimotor test battery
Note: The pole test was one of multiple sensorimotor tests used to detect alterations in the nigrostriatal dopaminergic system
View evidence from paper
“examined the motor deficits in ASO mice with a battery of sensorimotor tests that are sensitive to alterations in the nigrostriatal dopaminergic system”