Source Paper
Hyperactivity and Intact Hippocampus-Dependent Learning in Mice Lacking the M<sub>1</sub>Muscarinic Acetylcholine Receptor
Tsuyoshi Miyakawa, Masahisa Yamada, Alokesh Duttaroy, Jürgen Wess
Journal of Neuroscience • 2001
Porsolt Forced Swim Test
Objective: Measurement of depression-like behavior through immobilization time in water during the Porsolt forced swim test
This is a Porsolt Forced Swim Test protocol using mouse as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 2001 paper published in Journal of Neuroscience.
Model and subjects
mouse • Not explicitly stated • unknown • Not explicitly stated • Not explicitly stated
Study window
Estimated timing pending
Core workflow
Conduct Porsolt forced swim test
Primary readouts
- Immobilization time in water
- Depression-like behavior
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Conduct Porsolt forced swim test
Subject mice to the Porsolt forced swim test to measure immobilization time as a behavioral indicator of depression-like behavior
Note: The test measures reduced immobilization as an outcome variable
View evidence from paper
“M1R−/− mice showed reduced immobilization in the Porsolt forced swim test”