Prepulse Inhibition and Acoustic Startle Test
behavioralmouseYAC128
Objective: Measurement of sensorimotor gating through assessment of prepulse inhibition and habituation to acoustic startle stimuli in YAC128 mice
Materials & Equipment Checklist
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Protocol Steps
1
Prepulse Inhibition and Acoustic Startle Testing
YAC128 mice and wild-type controls were tested for prepulse inhibition and habituation to acoustic startle stimuli at 12 months of age
not specifiednot specified
Note: Testing was conducted to assess sensorimotor gating deficits in the YAC128 mouse model of Huntington's disease
View evidence from paper
“At 12 months of age, YAC128 mice show decreased prepulse inhibition and habituation to acoustic startle.”