Source Paper
α7 Nicotinic Receptor Subunits Are Not Necessary for Hippocampal-Dependent Learning or Sensorimotor Gating: A Behavioral Characterization of <i>Acra7</i>-Deficient Mice
Richard Paylor, Michelle Nguyen, Jacqueline N. Crawley, James Patrick, Arthur Beaudet et al.
Learning & Memory • 1998
Prepulse Inhibition Paradigm
behavioralmouseAcra7 homozygous mutant mice and wild-type littermates
Objective: Measurement of sensorimotor gating through prepulse inhibition of startle response in mice
Materials & Equipment Checklist
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Equipment1
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Protocol Steps
1
Prepulse Inhibition Testing
Acra7 mutant mice and wild-type littermates were tested in the prepulse inhibition paradigm to measure sensorimotor gating
Not specifiedNot specified
Note: This was one of three behavioral tests conducted on the animals
View evidence from paper
“Acra7 homozygous mutant mice and their wild-type littermates were tested in a Pavlovian conditioned fear test, for spatial learning in the Morris water task, and in the prepulse inhibition paradigm”