Repetitive Grooming Behavior Assay
Objective: Quantification of repetitive, stereotyped grooming behavior as a potential autism-relevant abnormality in NL1-deficient mice
This is a Repetitive Grooming Behavior Assay protocol using mouse as the model organism. The procedure involves 1 procedural steps. Extracted from a 2010 paper published in Journal of Neuroscience.
Model and subjects
mouse • NL1 knock-out (KO) mice and wild-type controls • unknown • Not specified in provided text • Not specified in provided text
Study window
Estimated timing pending
Core workflow
Grooming Behavior Observation
Primary readouts
- Frequency of repetitive grooming behavior
- Duration of grooming episodes
- Comparison between NL1 KO and wild-type mice
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Grooming Behavior Observation
Observe and quantify repetitive, stereotyped grooming behavior in NL1 KO mice as a measure of autism-relevant abnormality
Note: NL1 KO mice display a dramatic increase in repetitive, stereotyped grooming behavior compared to controls
View evidence from paper
“NL1 KO mice exhibit a dramatic increase in repetitive, stereotyped grooming behavior, a potential autism-relevant abnormality”