Repetitive Grooming Behavior Assay
behavioralmouseNL1 knock-out (KO) mice and wild-type controls
Objective: Quantification of repetitive, stereotyped grooming behavior as a potential autism-relevant abnormality in NL1-deficient mice
Protocol Steps
1
Grooming Behavior Observation
Observe and quantify repetitive, stereotyped grooming behavior in NL1 KO mice as a measure of autism-relevant abnormality
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Note: NL1 KO mice display a dramatic increase in repetitive, stereotyped grooming behavior compared to controls
View evidence from paper
“NL1 KO mice exhibit a dramatic increase in repetitive, stereotyped grooming behavior, a potential autism-relevant abnormality”