Rotarod Performance Test
Objective: Evaluation of motor coordination and balance using rotarod task
This is a Rotarod Performance Test protocol using mouse as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 2012 paper published in Journal of Neuroscience.
Model and subjects
mouse • Shank3 null mutant mice and wild-type controls • unknown • Not specified in provided text • Not specified in provided text
Study window
Estimated timing pending
Core workflow
Rotarod Performance Testing
Primary readouts
- Motor coordination performance
- Balance ability
- Time on rotating rod
- Latency to fall from rod
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Rotarod Performance Testing
Mice were tested on rotarod apparatus to assess motor coordination and balance. The test was conducted as part of behavioral phenotyping across three independent cohorts.
Note: Impaired rotarod performance was detected in homozygous null mutant mice and was consistent across all three independent cohorts tested, demonstrating replicability of this behavioral endophenotype.
View evidence from paper
“Impaired novel object recognition and rotarod performance were consistent across cohorts of null mutants.”