Rotarod Performance Test
Objective: Evaluation of motor coordination and balance using rotarod task
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Equipment1
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Protocol Steps
Rotarod Performance Testing
Mice were tested on rotarod apparatus to assess motor coordination and balance. The test was conducted as part of behavioral phenotyping across three independent cohorts.
Note: Impaired rotarod performance was detected in homozygous null mutant mice and was consistent across all three independent cohorts tested, demonstrating replicability of this behavioral endophenotype.
View evidence from paper
“Impaired novel object recognition and rotarod performance were consistent across cohorts of null mutants.”