Rotarod Performance Test
behavioralmouseGAT1 knockout (mGAT1 KO) mice
Objective: Assessment of motor coordination and balance in GAT1 knockout mice through rotarod performance testing
Materials & Equipment Checklist
1 item1 from ConductScience
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Equipment1
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Protocol Steps
1
Rotarod Performance Assessment
Mice were tested on the rotarod apparatus to measure motor coordination and balance. The test revealed reduced rotarod performance in GAT1 knockout mice compared to controls.
Not specifiedNot specified
Note: Reduced rotarod performance was one of the motor disorders observed in mGAT1 KO mice, along with gait abnormality and constant tremor
View evidence from paper
“Mouse GAT1 (mGAT1) KO mice exhibit motor disorders, including gait abnormality, constant 25-32 Hz tremor, which is aggravated by flunitrazepam, reduced rotarod performance”