Rotarod Test
behavioralmouseR6/2 transgenic
Objective: Assessment of motor performance and coordination in transgenic mice to evaluate neuroprotective effects of creatine supplementation
Materials & Equipment Checklist
1 item1 from ConductScience
Gather these items before starting the experiment. Check off items as you prepare.
Equipment1
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Protocol Steps
1
Rotarod motor performance testing
Mice were tested on the rotarod apparatus to assess motor performance and coordination as a measure of disease progression and treatment effects
Not specifiedNot specified
Note: Testing was conducted on transgenic R6/2 mice with and without creatine supplementation to compare motor performance outcomes
View evidence from paper
“Body weight and motor performance on the rotarod test were significantly improved in creatine-supplemented R6/2 mice”