Rotarod Test
Objective: Assessment of motor performance and coordination in transgenic mice to evaluate neuroprotective effects of creatine supplementation
This is a Rotarod Test protocol using mouse as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 2000 paper published in Journal of Neuroscience.
Model and subjects
mouse • R6/2 transgenic • unknown • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Rotarod motor performance testing
Primary readouts
- Motor performance on rotarod test
- Body weight
- Survival
- Brain atrophy development
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Rotarod motor performance testing
Mice were tested on the rotarod apparatus to assess motor performance and coordination as a measure of disease progression and treatment effects
Note: Testing was conducted on transgenic R6/2 mice with and without creatine supplementation to compare motor performance outcomes
View evidence from paper
“Body weight and motor performance on the rotarod test were significantly improved in creatine-supplemented R6/2 mice”