Social Behavior Assessment
Objective: Evaluation of social abnormalities in Shank3 mutant mice to assess behavioral deficits including social behavior, motor coordination, heat sensitivity, and novelty responses
This is a Social Behavior Assessment protocol using mouse as the model organism. The procedure involves 4 procedural steps. Extracted from a 2013 paper published in Journal of Neuroscience.
Model and subjects
mouse • Not specified in provided text • unknown • Not specified in provided text • Not specified in provided text
Study window
Estimated timing pending
Core workflow
Social Behavior Assessment • Motor Coordination Assessment • Heat Sensitivity Testing
Primary readouts
- Social abnormalities
- Motor-coordination deficits
- Hypersensitivity to heat
- Novelty avoidance
Key equipment and reagents
Verified items
0
Direct vendor links
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Protocol Steps
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Social Behavior Assessment
Evaluation of social abnormalities in mutant mice
Note: Mice exhibit minimal social abnormalities according to the study results
View evidence from paper
“these mice also exhibit motor-coordination deficits, hypersensitivity to heat, novelty avoidance, altered locomotor response to novelty, and minimal social abnormalities”
Motor Coordination Assessment
Testing of motor-coordination deficits in mutant mice
Note: Motor-coordination deficits were observed in the mutant mice
View evidence from paper
“these mice also exhibit motor-coordination deficits, hypersensitivity to heat, novelty avoidance, altered locomotor response to novelty, and minimal social abnormalities”
Heat Sensitivity Testing
Assessment of hypersensitivity to heat in mutant mice
Note: Hypersensitivity to heat was observed
View evidence from paper
“these mice also exhibit motor-coordination deficits, hypersensitivity to heat, novelty avoidance, altered locomotor response to novelty, and minimal social abnormalities”
Novelty Response Assessment
Evaluation of novelty avoidance and altered locomotor response to novelty
Note: Mice showed novelty avoidance and altered locomotor response to novelty
View evidence from paper
“these mice also exhibit motor-coordination deficits, hypersensitivity to heat, novelty avoidance, altered locomotor response to novelty, and minimal social abnormalities”