Social Interaction Task
Objective: Assessment of reciprocal social interactions in juvenile and adult mice to evaluate social impairments relevant to autism phenotypes
This is a Social Interaction Task protocol using mouse as the model organism. The procedure involves 2 procedural steps. Extracted from a 2012 paper published in Journal of Neuroscience.
Model and subjects
mouse • Shank3 null mutant and heterozygous mice • unknown • juvenile and adult • not specified in provided text
Study window
Estimated timing pending
Core workflow
Reciprocal Social Interaction Assessment • Three-Chambered Social Task
Primary readouts
- Reciprocal social interaction frequency and duration in juveniles
- Adult sociability performance on three-chambered task
- Presence or absence of social impairments
Key equipment and reagents
Verified items
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Direct vendor links
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Protocol Steps
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Reciprocal Social Interaction Assessment
Mild social impairments were detected, primarily in juveniles during reciprocal interactions
Note: Assessment conducted in juvenile mice with more pronounced deficits than in adults
View evidence from paper
“Mild social impairments were detected, primarily in juveniles during reciprocal interactions”
Three-Chambered Social Task
All genotypes displayed normal adult sociability on the three-chambered task
Note: Conducted in adult mice; no significant differences detected between genotypes
View evidence from paper
“all genotypes displayed normal adult sociability on the three-chambered task”