Social Novelty Preference Test
Objective: Assessment of preference for a novel unfamiliar mouse versus a familiar mouse to evaluate social novelty preference
This is a Social Novelty Preference Test protocol using mouse as the model organism. The procedure involves 3 procedural steps. Extracted from a 2006 paper published in Behavioural Brain Research.
Model and subjects
mouse • Multiple inbred strains tested including C57BL/6J, C57L/J, DBA/2J, FVB/NJ, C3H/HeJ, AKR/J, A/J, BALB/cByJ, BTBR T+tf/J, and 129S1/SvImJ • Male • Not specified • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Social Novelty Preference Test Setup • Habituation with Familiar Mouse • Social Novelty Preference Assessment
Primary readouts
- Preference for social novelty (comparison of interaction time with novel versus familiar mouse)
- Significant preference for social novelty (yes/no classification by strain)
Key equipment and reagents
Verified items
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Direct vendor links
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Protocol Steps
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Social Novelty Preference Test Setup
Test apparatus setup for assessing preference between a familiar mouse and a novel unfamiliar mouse
Note: The specific apparatus design, dimensions, and configuration are not detailed in the provided text
View evidence from paper
“Male mice from ten inbred strains were characterized in assays for sociability, preference for social novelty”
Habituation with Familiar Mouse
Mice are first exposed to a familiar mouse to establish baseline social interaction
Note: The duration and specific conditions of familiarization are not provided in the text
View evidence from paper
“preference for social novelty, and reversal of the spatial location of the reinforcer in T-maze and Morris water maze tasks”
Social Novelty Preference Assessment
Test subject is presented with choice between the familiar mouse and a novel unfamiliar mouse to measure preference for social novelty
Note: Specific test duration, measurement parameters, and behavioral metrics are not detailed in the provided text
View evidence from paper
“C57BL/6J, C57L/J, DBA/2J, FVB/NJ, BALB/cByJ, and BTBR T+tf/J showed significant preference for social novelty”