Social and Object Memory Testing
Objective: Assessment of social and object memory impairments in Adnp+/- mice and evaluation of NAP treatment effects on memory function
This is a Social and Object Memory Testing protocol using mouse as the model organism. The procedure involves 2 procedural steps, 1 materials. Extracted from a 2018 paper published in Journal of Clinical Investigation.
Model and subjects
mouse • Adnp+/- (haploinsufficient) • unknown • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Social and Object Memory Testing • NAP Treatment Administration
Primary readouts
- Social memory performance
- Object memory performance
- Reversal of memory impairments with NAP treatment
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Social and Object Memory Testing
Behavioral assessment of social and object memory in Adnp+/- mice
Note: Testing was conducted to evaluate memory impairments in the mutant mice
View evidence from paper
“Adnp+/- mice further exhibited global developmental delays, vocalization impediments, gait and motor dysfunctions, and social and object memory impairments”
NAP Treatment Administration
Daily NAP administration via systemic or nasal routes to evaluate treatment effects
Note: Treatment was administered systemically or via nasal route
View evidence from paper
“all of which were partially reversed by daily NAP administration (systemic/nasal)”