Source Paper
Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice
Dong W, Liu D, Fu S, Zhang J, Chen X et al.
Adv Sci (Weinh) • 2025
Subthreshold Social Defeat Stress
behavioralMouseNot specified
Objective: To induce mild stress that does not cause depression-like behavior on its own but can be used to test stress susceptibility when combined with other manipulations
Protocol Steps
1
Subthreshold Social Defeat Stress Administration
Administer subthreshold social defeat stress to mice
Not specified
View evidence from paper
“subjected them to subthreshold social defeat stress (SSDS)”
2
Behavioral Testing
Conduct behavioral assessments following SSDS treatment
Not specified
View evidence from paper
“subjected them to subthreshold social defeat stress (SSDS), and subsequently performed behavioral tests”