Swimming Platform Test
behavioralmouseYAC128 and wild-type controls
Objective: Measurement of time required to locate a platform in a swimming task to assess spatial learning and navigation
Materials & Equipment Checklist
1 item
Gather these items before starting the experiment. Check off items as you prepare.
Equipment1
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Protocol Steps
1
Swimming platform test
Mice are placed in a swimming pool and required to locate a submerged platform. The time taken to find the platform is measured as an indicator of spatial learning and navigation ability.
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Note: Test was conducted at 8 months of age and 12 months of age. YAC128 mice took longer to find the platform compared to wild-type controls beginning at 8 months of age.
View evidence from paper
“Additional support for cognitive dysfunction is evident in a simple swimming test in which YAC128 mice take longer to find the platform than wild-type (WT) controls beginning at 8 months of age”