Swimming T-Maze Test
Objective: Evaluation of spatial learning and cognitive flexibility through acquisition and reversal phases in a water-based T-maze, with particular focus on strategy-changing ability
Gather these items before starting the experiment. Check off items as you prepare.
Equipment1
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Protocol Steps
Acquisition Phase
Mice are trained to locate the platform in the swimming T-maze during the initial learning phase
Note: This phase tests spatial learning ability
View evidence from paper
“in a swimming T-maze test at this age”
Reversal Phase
The platform location is changed and mice must learn the new location, requiring cognitive flexibility and strategy change
Note: YAC128 mice take twice as long as wild-type controls to locate the platform in this phase
View evidence from paper
“in the reversal phase of the swimming T-maze test, YAC128 mice take twice as long as WT mice to locate the platform, indicating a difficulty in changing strategy”