Swimming T-Maze Test
Objective: Evaluation of spatial learning and cognitive flexibility through acquisition and reversal phases in a water-based T-maze, with particular focus on strategy-changing ability
This is a Swimming T-Maze Test protocol using mouse as the model organism. The procedure involves 2 procedural steps, 1 equipment items. Extracted from a 2005 paper published in Journal of Neuroscience.
Model and subjects
mouse • YAC128 and wild-type controls • unknown • 8 months and 12 months • Not specified
Study window
Estimated timing pending
Core workflow
Acquisition Phase • Reversal Phase
Primary readouts
- Time to find the platform during acquisition phase
- Time to find the platform during reversal phase
- Ability to change strategy between acquisition and reversal phases
- Comparison of performance between YAC128 and wild-type mice
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Acquisition Phase
Mice are trained to locate the platform in the swimming T-maze during the initial learning phase
Note: This phase tests spatial learning ability
View evidence from paper
“in a swimming T-maze test at this age”
Reversal Phase
The platform location is changed and mice must learn the new location, requiring cognitive flexibility and strategy change
Note: YAC128 mice take twice as long as wild-type controls to locate the platform in this phase
View evidence from paper
“in the reversal phase of the swimming T-maze test, YAC128 mice take twice as long as WT mice to locate the platform, indicating a difficulty in changing strategy”