Source Paper
Aerobic Exercise Promotes Hippocampal Neurogenesis and Ameliorates Cognitive Dysfunction Induced by Unilateral Labyrinthectomy
Zhou Z, Yu X, Tian E, Guo Z, Chen J et al.
CNS Neurosci Ther • 2026
T-Maze
behavioralMouseC57BL/6J
Objective: Assessment of spatial learning and memory by measuring preference for previously closed arm exploration
Materials & Equipment Checklist
4 items1 from ConductScience
Gather these items before starting the experiment. Check off items as you prepare.
Equipment3
Materials1
Not specified • Not specified
1 item available from ConductScience
Estimated: $1,190.00
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Protocol Steps
1
Pre-test acclimatization
Place mice in testing room for acclimatization
24 h
View evidence from paper
“mice were placed in the testing room 24 h before the experiment”
2
Learning phase
Only one arm of the T-maze (either left or right) is open, allowing mouse to freely explore
5 min
View evidence from paper
“only one arm of the T‐maze (either the left or the right) was open, allowing the mouse to freely explore the maze for 5 min”
3
Inter-trial interval
Return mouse to home cage between phases
30 min
View evidence from paper
“before returning to its home cage. Following a 30‐min interval”
4
Testing phase
Both arms of the T-maze are open and mouse is permitted to explore freely
5 min
View evidence from paper
“both arms of the T‐maze were open, and the mouse was permitted to explore the maze freely for another 5 min”