Source Paper
Prenatal and early postnatal cannabis exposure interactions with adolescent chronic stress on anxiety-like, depression-like, and risk-taking behaviour.
Peterson CS, Ifionu I, Hamood F, Semizeh H, Ali A et al.
Psychopharmacology (Berl) • 2026
Three Chamber Sociability Task
behavioralmouse
Objective: Measures social motivation including sociability and social novelty in mice
Materials & Equipment Checklist
1 item
Gather these items before starting the experiment. Check off items as you prepare.
Equipment1
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Protocol Steps
1
Subject preparation
Use offspring from dams that consumed THC during pregnancy and lactation, and were exposed to chronic mild unpredictable stress during adolescence
Note: Testing begins at PD58
View evidence from paper
“Mouse dams orally consumed 5 mg/kg THC in whole cannabis oil daily from GD1-PD10. Offspring were exposed to chronic mild unpredictable stress throughout adolescence (PD28-56). From PD58, mice were challenged with a battery of tests”
2
Conduct 3 chamber sociability and social novelty task
Perform the 3 chamber sociability and social novelty task as part of behavioral test battery
Note: Part of battery including anxiety-like, stress coping, anhedonia-like, and risk-taking behavior tests
View evidence from paper
“social motivation (3 chamber sociability and social novelty task)”