Toxicity Assessment
behavioralmouseAPP sw/0 transgenic mice (aged)
Objective: Evaluation of FPS-ZM1 toxicity in mice to assess safety profile of the RAGE-specific inhibitor
Materials & Equipment Checklist
1 item
Gather these items before starting the experiment. Check off items as you prepare.
Materials1
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Protocol Steps
1
FPS-ZM1 Administration and Toxicity Assessment
FPS-ZM1 was administered to mice and evaluated for toxicity. The compound was assessed for its ability to cross the blood-brain barrier and its safety profile in vivo.
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Note: FPS-ZM1 demonstrated nontoxic properties in mice during the study period
View evidence from paper
“FPS-ZM1 was nontoxic to mice and readily crossed the blood-brain barrier (BBB)”