Ultrasonic Vocalization Recording
Objective: Assessment of ultrasonic vocalizations as a measure of social communication in Shank3 mutant mice
This is a Ultrasonic Vocalization Recording protocol using mouse as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 2012 paper published in Journal of Neuroscience.
Model and subjects
mouse • Shank3 null and heterozygous mutants • unknown • Not explicitly stated • Not explicitly stated
Study window
Estimated timing pending
Core workflow
Ultrasonic vocalization assessment
Primary readouts
- Magnitude of ultrasonic vocalizations
- Presence or absence of ultrasonic vocalizations during social interactions
- Replicability of ultrasonic vocalization deficits across cohorts
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Ultrasonic vocalization assessment
Mice were assessed for ultrasonic vocalizations as a behavioral measure of social communication
Note: Reduced ultrasonic vocalizations were detected in some cohorts of null mutant mice but not consistently across all cohorts tested
View evidence from paper
“Reduced ultrasonic vocalizations, and deficits in reversal of water maze learning were detected only in some cohorts”