Ultrasonic Vocalization Recording
behavioralmouseShank3 null and heterozygous mutants
Objective: Assessment of ultrasonic vocalizations as a measure of social communication in Shank3 mutant mice
Materials & Equipment Checklist
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Gather these items before starting the experiment. Check off items as you prepare.
Equipment1
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Protocol Steps
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Ultrasonic vocalization assessment
Mice were assessed for ultrasonic vocalizations as a behavioral measure of social communication
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Note: Reduced ultrasonic vocalizations were detected in some cohorts of null mutant mice but not consistently across all cohorts tested
View evidence from paper
“Reduced ultrasonic vocalizations, and deficits in reversal of water maze learning were detected only in some cohorts”