Visual Cliff Avoidance
Objective: Test of visual perception and avoidance learning in which mice avoid crossing over a visual cliff
This is a Visual Cliff Avoidance protocol using mouse as the model organism. The procedure involves 2 procedural steps, 1 equipment items. Extracted from a 1999 paper published in Journal of Neuroscience.
Model and subjects
mouse • R6/2 transgenic and wild-type littermates • unknown • Between 3 and 14.5 weeks of age • Not specified
Study window
~14.5 week study window
Core workflow
Subject preparation and grouping • Visual cliff avoidance testing
Primary readouts
- Avoidance behavior over visual cliff
- Learning performance on visual cliff task
- Progressive deterioration in visual cliff avoidance between 3.5 and 8 weeks of age
Key equipment and reagents
Verified items
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Direct vendor links
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Protocol Steps
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Subject preparation and grouping
R6/2 transgenic mice and their wild-type littermates were used for behavioral testing. Separate groups of mice were used for each test including the visual cliff avoidance task.
Note: Testing was performed on mice between 3 and 14.5 weeks of age
View evidence from paper
“Behavioral testing was performed on R6/2 transgenic mice and their wild-type littermates between 3 and 14.5 weeks of age, using separate groups of mice for each test”
Visual cliff avoidance testing
Mice were tested on the visual cliff avoidance task to assess visual perception and avoidance learning capabilities
Note: Testing was part of a battery of cognitive tests including Morris water maze, two-choice swim tank, and T-maze
View evidence from paper
“between 3.5 and 8 weeks of age, R6/2 mice displayed progressive deterioration in specific aspects of learning in the Morris water maze, visual cliff, two-choice swim tank, and T-maze tasks”