Von Frey Filament Testing
Objective: Assessment of withdrawal threshold to mild mechanical stimulus using von Frey filaments to evaluate sensory response after spinal cord injury
This is a Von Frey Filament Testing protocol using mouse as the model organism. The procedure involves 1 procedural steps, 2 equipment items. Extracted from a 2008 paper published in Journal of Neuroscience.
Model and subjects
mouse • C1q knock-out (KO) and wild-type (WT) mice on BUB background • male • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Von Frey filament testing
Primary readouts
- Withdrawal threshold to mechanical stimulus
- Comparison of withdrawal response between C1q KO and WT mice
Key equipment and reagents
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Protocol Steps
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Von Frey filament testing
Assessment of withdrawal threshold to mild mechanical stimulus using von Frey filaments
Note: Testing was performed on both C1q KO and WT mice to measure sensory response
View evidence from paper
“decreased threshold for withdrawal from a mild stimulus using von Frey filament testing”