Working Memory Test
Objective: Evaluated working memory performance in COMT-Val-tg and COMT-null mice to assess the role of catechol-O-methyltransferase in cognitive function
This is a Working Memory Test protocol using mouse as the model organism. The procedure involves 1 procedural steps. Extracted from a 2008 paper published in Journal of Neuroscience.
Model and subjects
mouse • COMT-Val-tg and COMT-null mice • unknown • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Working Memory Assessment
Primary readouts
- Working memory performance
- Attentional set-shifting abilities
- Recognition memory
- Stress responses
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Working Memory Assessment
Evaluated working memory performance in COMT-Val-tg and COMT-null mice as part of behavioral testing
Note: Results showed impaired working memory in COMT-Val-tg mice and improved working memory in COMT-null mice
View evidence from paper
“Increased COMT enzyme activity in Val-tg mice resulted in disrupted attentional set-shifting abilities, and impaired working and recognition memory”