Source Paper
Sex-dependent effects of ultra-low-dose-THC preventive treatment on neuroinflammation and cognitive decline in 5xFAD mice
Nitzan K, Bentulila Z, Bregman-Yemini N, Ayalon N, David D et al.
Biol Sex Differ • 2026
Y-Maze
behavioralmice5xFAD mouse model and WT littermates
Objective: Evaluate short-term working memory (PFC-dependent task)
Materials & Equipment Checklist
4 items1 from ConductScience
Gather these items before starting the experiment. Check off items as you prepare.
Equipment3
Materials1
not specified • not specified
1 item available from ConductScience
Estimated: $4,900.00
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Protocol Steps
1
Mouse placement
Place mice initially in the middle of the Y-maze
not specified
View evidence from paper
“Mice were initially placed in the middle”
2
Recording arm entries
Record the sequence of arm entries for each mouse
8-min period
View evidence from paper
“the sequence of arm entries was recorded for each mouse over an 8-min period”
3
Arena cleaning
Clean the Y-maze arena with alcohol between mice to eliminate olfactory cues
not specified
View evidence from paper
“The arenas of the Y-maze, OFH and PLT were cleaned with Alcohol between mice, in order to eliminate olfactory cues”