Puech C, Badran M, Barrow MB, et al. International journal of molecular sciences 2025;26(5):1815.
The test records were read once by AI and checked by code. No person has reviewed them yet. How records are made
| Setting | Value | Paper’s words |
|---|---|---|
| Arm size |
| “two open arms and two closed arms (arm length 35 cm, wall height for closed arms 20 cm)” “A 0.5 cm height wall was added to the open arms” |
| Maze elevation |
| “The device is situated 56 cm above the floor” |
| Session duration |
| “allowed to explore the maze for 5 min” |
| Not in the Methods | Illumination | |
| Other settings in the paper | ||
| Elevated cross | two open arms and two closed arms | “an elevated cross formed by two open arms and two closed arms” |
| Made of | blue Plexiglas | “made of blue Plexiglas radiating from a central platform” |
| Placed | in the central area facing one open arm | “The animals were placed in the central area facing one open arm” |
| Considered | the open arms as well as the center zone | “we considered the open arms as well as the center zone” |
| Cleaned with | 70% ethanol | “the experimental set-ups were cleaned with 70% ethanol to prevent odor cues” |
| Conducted | between 9 a.m. and 5 p.m. | “conducted by three observers between 9 a.m. and 5 p.m.” |
| Observers | three | “conducted by three observers between 9 a.m. and 5 p.m.” |
| Operators | blinded to the exposure | “performed by operators who were blinded to the exposure” |
| Recorded | from a vertical point of view | “The tests were recorded from a vertical point of view with a video camera suspended above the experimental area” |
| Apparatus | ||
| Mazes | Maze Engineers | “All the mazes were purchased from Maze Engineers (Cambridge, MA, USA)” |
| Video camera | “The tests were recorded from a vertical point of view with a video camera suspended above the experimental area” | |
| Noldus Ethovision XT17 Software | “All the experiments were interfaced with a video tracking system (Noldus Ethovision XT17 Software, Leesburg, VA, USA)” | |
| Setting | Value | Paper’s words |
|---|---|---|
| Arena size, illumination |
| “The NOR test has been previously extensively described [32,64,65,70]” |
| Session duration |
| “The animals were allowed to explore the open field for 10 min” “The habituation phase allows mice to explore the open field for 10 min” |
| Other settings in the paper | ||
| Locomotor activity monitored | the first 5 min | “with locomotor activity monitored during the first 5 min” |
| Placed | in the center | “mice were placed in the center of a blue opaque open-field plastic chamber” |
| Chamber | blue opaque open-field plastic | “a blue opaque open-field plastic chamber” |
| Cleaned with | 70% ethanol | “the experimental set-ups were cleaned with 70% ethanol to prevent odor cues” |
| Conducted | between 9 a.m. and 5 p.m. | “conducted by three observers between 9 a.m. and 5 p.m.” |
| Observers | three | “conducted by three observers between 9 a.m. and 5 p.m.” |
| Operators | blinded to the exposure | “performed by operators who were blinded to the exposure” |
| Recorded | from a vertical point of view | “The tests were recorded from a vertical point of view with a video camera suspended above the experimental area” |
| Apparatus | ||
| Video camera | “The tests were recorded from a vertical point of view with a video camera suspended above the experimental area” | |
| Noldus Ethovision XT17 Software | “All the experiments were interfaced with a video tracking system (Noldus Ethovision XT17 Software, Leesburg, VA, USA)” | |
| Blue opaque open-field plastic chamber | “mice were placed in the center of a blue opaque open-field plastic chamber” | |
| Methods cited to other work | ||
| The NOR test procedure, whose habituation phase is this open field session | [32,64,65,70] | |