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Papers/Somebang et al. 2021

CCR2 deficiency alters activation of microglia subsets in traumatic brain injury

Somebang K, Rudolph J, Imhof I, et al. Cell reports 2021;36(12):109727.

The test records were read once by AI and checked by code. No person has reviewed them yet. How records are made

Tests in this paper

  • Morris water maze test
  • Open field test
  • Rotarod test

Morris water maze test

Compare with 2 other papers
SettingValuePaper’s words
Trial duration
  • 60 s

“The maximum time per trial was 60 s.”
Number of trials
  • three trials per session

“three trials per session for two sessions in one day”
Not in the MethodsPool size, water temperature, platform size, platform depth below the surface
Other settings in the paper
Version

cued platform

“The cued platform version”
Post-TBI

4 weeks

“starting at 4 weeks post-TBI”
Water

opaque

“filled with opaque water”
Platform

a cue on top

“A platform with a cue on top”
Sessions

two sessions in one day

“three trials per session for two sessions in one day”
A handler blinded to the animal group would guide the animal to the platform

after 60 s

“If an animal had not located the platform after 60 s, a handler blinded to the animal group would guide the animal to the platform.”
Apparatus
Swimming pool

Maze Engineers

“A swimming pool (Maze Engineers)”
Ethovision XT13

Noldus, RRID:SCR_000441

“Ethovision XT 13 | Noldus | RRID:SCR_000441”
Platform with a cue on top
“A platform with a cue on top was placed in opaque water.”
Methods cited to other work
The cued platform version of the test as a whole; only citations follow the test name, with no wording such as "as described"

Liu et al., 2007, Raber et al., 2004, Suh et al., 2005, Hong et al., 2007, Hsieh et al., 2014

“The cued platform version of the Morris Water Maze(Liu et al., 2007, Raber et al., 2004, Suh et al., 2005, Hong et al., 2007, Hsieh et al., 2014)”
Rank summary scores

Possin et al., 2016

“Rank summary scores(Possin et al., 2016)”

Open field test

Compare with 10 other papers
SettingValuePaper’s words
Arena size
  • 40 × 40 inches

“inside a plexiglass enclosure (40 × 40 inches)”
Session duration
  • 10 min/day

“Animals were tested for 10 min/day for two days.”
Not in the MethodsIllumination
Other settings in the paper
Post-TBI

3 weeks

“starting at 3 weeks post-TBI”
Animals were tested

two days

“Animals were tested for 10 min/day for two days.”
Apparatus
Plexiglass enclosure
“inside a plexiglass enclosure (40 × 40 inches)”
Automated infrared photocells
“surrounded by automated infrared photocells”
Computer
“connected to a computer with KinderScientific software”
KinderScientific software

Hamilton & Kinder

“KinderScientific software (Hamilton & Kinder) to record data”
Methods cited to other work
The test as a whole; only citations follow the test name, with no wording such as "as described"

Hong et al., 2007, Raber et al., 2004, Suh et al., 2005, Hsieh et al., 2014

“The open field test(Hong et al., 2007, Raber et al., 2004, Suh et al., 2005, Hsieh et al., 2014)”

Rotarod test

Compare with 9 other papers
SettingValuePaper’s words
Rod speed
  • 40 rpm

“a rotating rod that accelerated to 40 rpm over 300 s”
Number of trials
  • five trials/day

“Animals were assessed five trials/day for two days.”
Not in the MethodsTrial duration
Other settings in the paper
Accelerated to 40 rpm over

300 s

“a rotating rod that accelerated to 40 rpm over 300 s”
After TBI

three weeks

“three weeks after TBI”
Animals were assessed

two days

“Animals were assessed five trials/day for two days.”
Apparatus
Rotarod

TSE Systems

“Rotarod (Hong et al., 2007, Hsieh et al., 2014, Liu et al., 2007, Raber et al., 2004, Suh et al., 2005) (TSE Systems)”
Methods cited to other work
The test as a whole; only citations follow the test name, with no wording such as "as described"

Hong et al., 2007, Hsieh et al., 2014, Liu et al., 2007, Raber et al., 2004, Suh et al., 2005

“Rotarod (Hong et al., 2007, Hsieh et al., 2014, Liu et al., 2007, Raber et al., 2004, Suh et al., 2005)”

Tests in this paper

  • Morris water maze test
  • Open field test
  • Rotarod test

The paper

Species: mice

“WT C57BL/6 male (RRID:IMSR_JAX:000664) cage mate mice (aged 12-16 weeks)”
Read the paper (doi:10.1016/j.celrep.2021.109727)Full text on PubMed Central (PMC8594931)

Quotes are shown under the paper’s CC BY license.

How far this was checked

The test records were read once by AI and checked by code. No person has reviewed them yet.

How records are made