Source Paper
Lack of striatal-enriched protein tyrosine phosphatase affected the serotonin system, behavior, and brain morphology in mice
Moskaliuk V, Komleva P, Khotskin N, Arefieva A, Shevelev O et al.
Front Psychiatry • 2026
Novel Object Recognition Test
Objective: To test for the memory performance of mice
This is a Novel Object Recognition Test protocol using mice as the model organism. The procedure involves 3 procedural steps, 1 equipment items, 1 materials. Extracted from a 2026 paper published in Front Psychiatry.
Model and subjects
mice • C57BL/6-Ptpn5_KO and C57BL/6 • male • 2-month-old • not specified
Study window
Estimated timing pending
Core workflow
Follow established protocol • Record time spent with objects • Calculate novelty index
Primary readouts
- Novelty index (percentage)
- Time spent with new object
- Time spent with familiar object
Key equipment and reagents
Use this page as an execution guide, then fall back to the source paper whenever you need exact exclusions, dosing details, or assay-specific caveats.
Confirm first
- Verify the animal model, intervention setup, and collection timepoints against the source paper.
- Check that every direct vendor link matches the exact specification your lab plans to run.
Use the page like this
- Work through the protocol steps in order and use the inline vendor chips only when you need to source or verify an item.
- Jump to Experimental Context for readouts, data shape, and analysis flow before planning downstream analysis.
Protocol Steps
Start here. The step list is optimized for running the experiment, with direct vendor links available inline when you need to source a cited item.
Follow established protocol
Conduct the novel object recognition test following previously described procedures
View evidence from paper
“We followed the previously described procedure”
Record time spent with objects
Automatically register the time spent near objects during the test
View evidence from paper
“The time spent near the objects was registered automatically”
Calculate novelty index
Calculate novelty index using the formula for time spent with new versus familiar objects
View evidence from paper
“time spent with new object (No)/[time spent with new object (No) + time spent with familiar object (Fo)] × 100%”