Source Paper
Lack of striatal-enriched protein tyrosine phosphatase affected the serotonin system, behavior, and brain morphology in mice
Moskaliuk V, Komleva P, Khotskin N, Arefieva A, Shevelev O et al.
Front Psychiatry • 2026
Novel Object Recognition Test
behavioralmiceC57BL/6-Ptpn5_KO and C57BL/6
Objective: To test for the memory performance of mice
Protocol Steps
1
Follow established protocol
Conduct the novel object recognition test following previously described procedures
View evidence from paper
“We followed the previously described procedure”
2
Record time spent with objects
Automatically register the time spent near objects during the test
View evidence from paper
“The time spent near the objects was registered automatically”
3
Calculate novelty index
Calculate novelty index using the formula for time spent with new versus familiar objects
View evidence from paper
“time spent with new object (No)/[time spent with new object (No) + time spent with familiar object (Fo)] × 100%”