Source Paper
Lack of striatal-enriched protein tyrosine phosphatase affected the serotonin system, behavior, and brain morphology in mice
Moskaliuk V, Komleva P, Khotskin N, Arefieva A, Shevelev O et al.
Front Psychiatry • 2026
Social Interaction Test
behavioralmiceC57BL/6-Ptpn5_KO and C57BL/6 (wild type)
Objective: To evaluate social behavior by measuring duration of social contacts between test mouse and juvenile intruder
Materials & Equipment Checklist
3 items1 from ConductScience
Gather these items before starting the experiment. Check off items as you prepare.
1 item available from ConductScience
Estimated: $9,900.00
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Protocol Steps
1
Introduce juvenile intruder
Place a 4-week-old juvenile Balb/c male into the home cage of the test mouse
View evidence from paper
“A juvenile Balb/c male (4 weeks old) was introduced to the home cage of the tested male”
2
Record social interactions
Monitor and register social interactions for 10 minutes using EthoStudio software
View evidence from paper
“During 10 min, social interactions were registered with the EthoStudio software”
3
Measure social behavior
Evaluate social behavior as the total duration of social contacts including intruder's head and body sniffing
View evidence from paper
“Social behavior was evaluated as the total duration of social contacts (intruder's head and body sniffing)”