Source Paper
Lack of striatal-enriched protein tyrosine phosphatase affected the serotonin system, behavior, and brain morphology in mice
Moskaliuk V, Komleva P, Khotskin N, Arefieva A, Shevelev O et al.
Front Psychiatry • 2026
Startle Test
Objective: To measure acoustic startle response magnitude and prepulse inhibition in mice
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Protocol Steps
Perform startle test after rest period
The startle test was performed after 1 month of rest following other behavioral tests
View evidence from paper
“After 1 month of rest, the startle test was performed”
Conduct six test sessions
The test consisted of six sessions, each including either a single pulse (P) or a pulse with a prepulse (PP)
View evidence from paper
“The test consisted of six sessions, each of which included either a single pulse (P) or a pulse with a prepulse (PP)”
Measure startle response
Measure the magnitude of acoustic startle response using accelerometer sensor starting 20 ms after the main signal
View evidence from paper
“The magnitude of an acoustic startle response was measured with an accelerometer sensor starting 20 ms after the main signal”
Calculate final parameter
Take the average potential throughout the measurement as the final parameter
View evidence from paper
“The average potential throughout the measurement was taken as the final parameter”