Source Paper
Lack of striatal-enriched protein tyrosine phosphatase affected the serotonin system, behavior, and brain morphology in mice
Moskaliuk V, Komleva P, Khotskin N, Arefieva A, Shevelev O et al.
Front Psychiatry • 2026
Three-Chambered Social Approach Test
behavioralmiceC57BL/6-Ptpn5_KO and C57BL/6 (wild type)
Objective: To evaluate a mouse's sociability
Materials & Equipment Checklist
3 items
Protocol Steps
1
Researcher exits room
The researcher leaves the testing room during the experiment
View evidence from paper
“During the time of testing, the researcher left the room”
2
Record movement and chamber time
Track mouse movement using 3D sensor and record time spent in each chamber
View evidence from paper
“Movement tracking was performed with Kinect 3D sensor connected to the PC through the USB-2 port”
3
Clean equipment between tests
Clean the device and all materials with wet and dry napkins between tests
View evidence from paper
“Between tests, the device and all used materials were cleaned with wet (H2O2) and dry napkins”